Light chain myeloma sometimes called Bence Jones myelomaĪbout 15 out of 100 people with myeloma (15%) do not produce complete immunoglobulins. The next most common is IgA and light chain only. The type of immunoglobulin this is varies from person to person. Only one type of immunoglobulin (Ig) is overproduced when you have myeloma. Your type of myeloma is named after the abnormal immunoglobulin it is making. Immunoglobulins can be classified into one of 5 types depending on their heavy chains. ![]() As well as the whole immunoglobulin, often a small part called the free light chain (called Bence Jones protein in urine) is made in big amounts by the plasma cells.Įach immunoglobulin is made up of 2 long protein chains (called heavy chains) and 2 shorter protein chains (called light chains). These proteins are called immunoglobulin (also called abnormal protein, paraprotein, monoclonal protein or monoclonal spike). Most people have a type of myeloma that causes the abnormal plasma cells to produce abnormal proteins. To understand about the different types of myeloma, it is helpful to know about plasma cells and immunoglobulins. Some of these conditions can develop into myeloma. ![]() For example, MGUS, plasmacytoma and amyloidosis. There are also some other conditions related to myeloma. These include light chain myeloma and non secretory myeloma. There are different types and subtypes of myeloma.
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